Plumes of smoke rise from the area of a UPS cargo plane crash at Louisville Muhammad Ali International Airport on Nov. 4. (Jon Cherry/AP)
November 5, 2025 9:40 AM, EST
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LOUISVILLE, Ky. — First responders are searching for more victims Nov. 5 after a UPS cargo plane crashed and exploded in a massive fireball at the company’s global aviation hub in Kentucky, killing at least nine people and injuring 11, authorities said.
The plane crashed about 5:15 p.m. Nov. 4 as it was departing for Honolulu from UPS Worldport at Louisville Muhammad Ali International Airport in Louisville.
Kentucky Gov. Andy Beshear posted online Nov. 5 that 16 families who gathered at a reunification center “have reported loved ones unaccounted for.”
The airport is 7 miles from downtown Louisville, close to the Indiana state line, residential areas, a water park and museums. Emergency officials initially put out a shelter-in-place order for a 5-mile (8-kilometer) radius. By the morning of Nov. 5, that was reduced to a quarter of a mile radius, as officials monitored the air quality,
Kentucky, more heartbreaking news out of Louisville. The number of those lost has now risen to at least 9, with the possibility of more. Right now these families need prayers, love and support. Let’s wrap our arms around them during this unimaginable time.
— Governor Andy Beshear (@GovAndyBeshear) November 5, 2025
Over 200 emergency workers responded to the crash Nov. 4, Louisville Mayor Craig Greenberg said.
“We’ll continue to put every resource we have available to this, as well,” he told WLKY-TV on the morning of Nov. 5.
Video showed flames on the plane’s left wing and a trail of smoke. The plane then lifted slightly off the ground before crashing and exploding in flames. Video showed portions of a building’s shredded roof next to the end of the runway.
Beshear said he didn’t know the status of the three crew members aboard the plane, a McDonnell Douglas MD-11 made in 1991. It wasn’t immediately clear if they were being counted among the dead.
‘We All Know Somebody Who Works at UPS’
Beshear said he expects the death toll to increase. Eleven people were also hurt. Beshear said two of the injured are in critical care.
Surveillance video shows fiery explosion as UPS plane rips through Kentucky businesses | Click on the image to read the full story https://t.co/zA7SN3fK4E
— WBAL-TV 11 Baltimore (@wbaltv11) November 5, 2025
“Anybody who has seen the images, the video, knows how violent this crash is,” he said.
The Louisville package handling facility is the company’s largest, and UPS announced late Nov. 4 that package sorting at the center was halted. It didn’t say when operations would resume. The hub employs thousands of workers, has 300 daily flights and sorts more than 400,000 packages an hour.
“We all know somebody who works at UPS,” Louisville Metro Council member Betsy Ruhe said. “And they’re all texting their friends, their family, trying to make sure everyone is safe. Sadly, some of those texts are probably going to go unanswered.”
Missing Loved Ones
Eric Richardson stood outside a police training academy, where people gathered waiting for word of their missing loved ones Nov. 4. He said was hoping for information about his girlfriend, who had been at a metal recycling business near the explosion and wasn’t answering her phone. Her phone’s live location said she was still there.
We will release more facts as they become available at https://t.co/8Y3csuvvgZ pic.twitter.com/qfbiACQ3vY
— UPS (@UPS) November 5, 2025
Bobby Whelan, Richardson’s friend, had been in front of her in line, but had left minutes before the explosion. He said he was about a quarter of a mile down the road when he heard what sounded like a bomb exploding.
“We don’t even want to think about anything but the best,” Whelan said. “All our friends were there.”
The governor said a business, Kentucky Petroleum Recycling, appeared to be “hit pretty directly,” and a nearby auto parts operation was also affected.
Tom Brooks Jr., who runs a metal recycling business down the street, said the unbelievable magnitude of the crash “just rocked the whole place.”
“This was massive. I mean, it literally looked like a war zone,” he said.
Destyn Mitchell was working as a host at an Outback restaurant, about a 15-minute drive from the crash, when she heard a loud boom.
“People who just sat down to eat got up and left in under 30 minutes and packed up their food because they wanted to hurry up and get home,” she said.
What Happened to the Plane?
Pablo Rojas, an aviation attorney, said that based on videos of the crash the aircraft appeared to be struggling to gain altitude as a fire blazed on its left side around one of its engines. Given the fuel the plane was carrying, it was only a matter of time before the blaze spread rapidly or an explosion happened.
“Really the plane itself is almost acting like a bomb because of the amount of fuel,” he said.
At this time, Runway 11/29 is open at SDF and the airport is available for aircraft operations. TSA screening remains on-going this morning for departing passengers. Anyone scheduled to depart or arrive at SDF today is encouraged to closely monitor their flight status as delays…
— FlyLouisville (SDF) (@FlyLouisville) November 5, 2025
Greenberg said the National Transportation Safety Board has sent a 28-strong crew to investigate the crash.
The airport, which also shut down for the night, resumed operations Nov. 5, with at least one runway open. Flights that were canceled Nov. 4 were scheduled to depart and arrive first. Some flights previously scheduled to take off from the airport in the morning were canceled.
Some stranded passengers spent the night in the airport, and nearby roads remained closed Nov. 5. A public school district in Louisville canceled classes and activities for the day.
Written by Bruce Schreiner, Hallie Golden and Dylan Lovan. Golden reported from Seattle. AP reporters Ed White in Detroit, John Raby in Cross Lanes, West Virginia, Adrian Sainz in Memphis, Tennessee, and Kathy McCormack in Concord, New Hampshire, contributed to this report.
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